白喉毒素蛋白

产品名称	Diphtheria toxin Protein
产品货号	DTD01
产品规格
价格

产品详情

名称	Diphtheria toxin, Corynephage beta
纯度	≥ 95% by SDS-PAGE.
表达宿主	E.coli
序列	MGADDVVDSS KSFVMENFSS YHGTKPGYVD SIQKGIQKPK SGTQGNYDDD WKGFYSTDNK HDAAGYSVDN ENPLSGKAGG VVKVTYPGLT KVLALKVDNA ETIKKELGLS LTEPLMEQVG TEEFIKRFGD GASRVVLSLP FAEGSSSVEY INNWEQAKAL SVELEINFET RGKRGQDAKY EYMAQACAGN RVRRSVGSSL SCINLDWDVI RDKTKTKIES LKEHGPIKNK MSESPNKTVS EEKAKQYLEE FHQTALEHPE LSELKTVTGT NPVFAGANYA AWAVNVAQVI DSETADNLEK TTAALSILPG IGSVMGIADG AVHHNTEEIV AQSIALSSLM VAQAIPLVGE LVDIGFAAYN FVESIINLFQ VVHNSYNRPA YSPGHKTQPF LHHHHHH
分子量	43 kDa
标签	C-His
内毒素	<1 EU/μg
缓冲液	1×PBS, pH 7.4.
稳定性 & 储存条件	Freeze dried powder can be stored at 4℃ for three years. Used within 2-4 weeks after reconstitution, can be stored at 4℃ for 3 years at -20℃.
SDS-PAGE
Western Blot

产品说明书产品说明书

Diphtheria toxin is an exotoxin released by Corynebacterium diphtheriae, which has toxic molecules and is the main pathogenic substance causing diphtheria disease.

There are three structural regions: the N-terminus is the catalytic region, the middle is the transmembrane region, and the C-terminus is the receptor binding region. Under the action of trypsin, diphtheria toxin is degraded into A fragment and B fragment. DTA is the enzyme active region of diphtheria toxin and a key structural domain of DT type immunotoxins, which inhibits protein synthesis by catalyzing ADP ribosylation on chain elongation factor 2. However, Escherichia coli chain elongation factor G is not affected by this, so some diphtheria expression plasmids based on DTA fragments can be amplified in engineered bacteria. DTA protein and its monoclonal antibodies have important value in the study of the toxicity mechanism, detection, and purification of immunotoxins. At the same time, by utilizing its characteristic of producing specific immunity, it can be used to make targeted drugs. In early anti infection treatment, toxoid vaccines made from diphtheria toxin can be used for the prevention of the disease.

物流平台：默认为顺丰速运。若有其他需求，请联系对接销售。
发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。